Iranian Biology Society Journal of Plant Research (Iranian Journal of Biology) 2383-2592 27 2 2014 08 23 Effect of diferent levels of N fertilization on Yield and Amount of Alkaloids vincristine and vinblastine in Periwinkle (Cataharanthus roseus L.G.Don) Effect of diferent levels of N fertilization on Yield and Amount of Alkaloids vincristine and vinblastine in Periwinkle (Cataharanthus roseus L.G.Don) 269 275 363 27210 FA Journal Article 2010 12 27 Periwinkle (Catharanthus roseus (L. ) G. Don), a medicinal plant, which economiclly is highly valued because of  its anti-cancer lalkaloids of  vincristine and vinblastine. Since the availability of nitrogen (N) is expected to play an important role in the biosynthesis and accumulation of alkaloids in plants, the effect of N fertilization on the content of alkaloids of periwinkle was studied. the four levels of 0, 100, 150, 200 kg/ha N fertilization in a bulok completely randomized design with three replications. N fertilization significantly increased the content of alkaloids in leaves. This study showed that  by increasing N fertilization dry weight increased. The highest level  of alkaloid vincristine was in the 0 kg/ha of N fertilization and  the highest level alkaloid vinblastine was in the 200 kg/ha of N fertilization.<span lang="FA"> </span> Periwinkle (Catharanthus roseus (L. ) G. Don), a medicinal plant, which economiclly is highly valued because of  its anti-cancer lalkaloids of  vincristine and vinblastine. Since the availability of nitrogen (N) is expected to play an important role in the biosynthesis and accumulation of alkaloids in plants, the effect of N fertilization on the content of alkaloids of periwinkle was studied. the four levels of 0, 100, 150, 200 kg/ha N fertilization in a bulok completely randomized design with three replications. N fertilization significantly increased the content of alkaloids in leaves. This study showed that  by increasing N fertilization dry weight increased. The highest level  of alkaloid vincristine was in the 0 kg/ha of N fertilization and  the highest level alkaloid vinblastine was in the 200 kg/ha of N fertilization.<span lang="FA"> </span> https://plant.ijbio.ir/article_363_00411460f7c92d2124a67ea0f4cb5f85.pdf